I've been reading the Star Trek tie-in novels, off and on, for decades. I don't know that I've read one where Pulaski was the main character before - or if I have, I've forgotten it. I liked her in TNG, for the year that she was there, so it was good to read a novel where she's the main doctor instead of Crusher. To mix it up even more, she's on a mercy mission to DS9, where a new version of the plague is affecting Bajorans, Cardassians, and even Ferengi. I liked her interactions with Dukat, and would have enjoyed more of them. 

I do think, however, that this mini-series is already at risk of being a little repetitive: mysterious figure doses a random location with contagion, and a Starfleet doctor takes the lead in curing it, at which point the mysterious figure basically rubs their murdering hands together and thinks "I'll do better next time!" Hopefully book three breaks the pattern a bit.

Finally, although I always enjoy Kira - she was one of the best characters on DS9 - I wonder if her subplot here was really necessary. It didn't seem to do much, or to illuminate her character any.